Shiseido's Clinical Trial Shows Retinol Products Improve Skin Wrinkles

Retinol active ingredients have “positive effect and efficacy” in improving skin wrinkles, according to Shiseido. Results of a clinical trial conducted by the beauty brand revealed that “retinol-formulated products” come with features that improve skin wrinkles. With Japanese women aged 37-54 who had shallow to deep wrinkles at their eye corners as study subjects, the clinic trial involved the women using the products for nine weeks. After the usage period, skin wrinkles showed improvement compared with those of women who used non-retinol products.